Forumi Horizont (http://www.forumihorizont.com/index.php3)
- Mjekësia (http://www.forumihorizont.com/forumdisplay.php3?forumid=266)
-- medical sciences (shkencat mjeksore) (http://www.forumihorizont.com/showthread.php3?threadid=8624)

the cause of the pain

Cod. A20072005

the painfull mestruations (called dysmenorrea)is a common situation that affects nearly 50% of the adult women.it can be classified as primary and secondary.still noone knows the cause of the primary dysmenorrea that affects the women with an ovulatory mestrual cycle.the strong pain,caused by the contraction if the uterine smooth muscle ,is a result of prostaglandin formation from the secretive endometrium and their release during the fall of the endometrium cells.other symptoms are related to this situation,like cefalea,nausea,diarrea and in cases of severe pain even vomit.in these severe cases the pain starts in the pelvic region and irradiate in the vertebral column,lumbar zone and legs.

the secondary mestrual pains are mostly caused by the use of contraceptives and some kind of situations like endometriosis.
in more than 80% of the cases the use of prostaglandin formation inhibitors is able to decrease the pain intensity(the mecchanism is the same as that of aspirine: blockin the enzime COX1 and 2 can stop the formation of prostaglandin.

most probably the prostaglandin formation doesn't happen or is smaller in the other 50% so the pain si not present.